Pleiotropic role of IL-5 across diseases
IL-5 directly involves and affects several target cells, including eosinophils and B cells, inducing cell proliferation, survival and differentiation, making it a key factor in the inflammatory process in asthma, Chronic Rhinosinusitis with Nasal Polyps (CRSwNP), Eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES). Understanding this inflammatory phenomenon and its specific treatment options is essential for the management of patients and their comorbidities.
This webinar will comprehensively address the full complexity of IL-5 and its mechanism of action.
Learning Objectives
- To develop the concept of immune response and its mechanisms
- To put the focus on IL-5 as a modulator of response
- To understand the biological effects of IL-5 and the broader role beyond eosinophilic inflammation
- To link Type 2 inflammation with respiratory diseases
- To interpret the mechanism of action of biologics
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